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Triple Negative Breast Cancer Treatment Market

(New York, USA) DelveInsight’s “Triple Negative Breast Cancer Market Insights, Epidemiology, and Market Forecast-2034” report delivers an in-depth understanding of Triple Negative Breast Cancer, historical and forecasted epidemiology as well as the Triple Negative Breast Cancer market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The Triple Negative Breast Cancer market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Triple Negative Breast Cancer market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Triple Negative Breast Cancer treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Triple Negative Breast Cancer market.

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Some facts of the Triple Negative Breast Cancer Market Report are:

• According to DelveInsight, Triple Negative Breast Cancer market size is expected to grow at a CAGR of 4.7% by 2034.
• According to DelveInsight’s analysis, the TNBC market in the 7MM was valued at approximately USD 4,200 million in 2023. Over the forecast period from 2025 to 2034, Triple Negative Breast Cancer market is projected to grow at a CAGR of 4.7%.
• Leading Triple Negative Breast Cancer companies working in the market are Johnson & Johnson Private Limited, Cipla Inc, Abbott, AbbVie Inc, Merck KGaA, Sun Pharmaceutical, Aurobindo Pharma, Lupin, Hikma Pharmaceuticals PLC, Amneal Pharmaceuticals LLC., Pfizer Inc, Mylan N.V., Novartis AG, Bristol-Myers Squibb Company, GSK plc, Bayer AG, AstraZeneca, Gilead Science, Infinity Pharmaceuticals, HiberCell, Immunomedics, HiberCell, CytoDyn, and Many Others.
• Higher Indulgence in Immunotherapy and Growing Demand for Hospitals are some of the factors driving the Triple Negative Breast Cancer Market growth.
• Leronlimab (Cytodyn) has also received fast track designation by the US FDA which clearly suggests the fast growth of TRIPLE NEGATIVE BREAST CANCER market in the forecast period (2025–2034).
• In May 2025, UTR Therapeutics Inc. announced it had submitted an Investigational New Drug (IND) application to the FDA for UTRxM1-18, an innovative therapy aimed at treating c-MYC driven cancers such as triple-negative breast, pancreatic, colorectal, and ovarian cancers. Built on its proprietary 3’UTR engineering platform, UTRxM1-18 works by selectively degrading cancer-specific transcripts while preserving healthy cells. Preclinical data demonstrated robust, dose-dependent antitumor activity across multiple cancer types, without any dose-limiting toxicities.
• Also in May 2025, Lantern Pharma Inc. disclosed it received FDA clearance for its IND to initiate a Phase 1b/2 clinical trial of LP-184 in triple-negative breast cancer. This regulatory milestone follows the company’s prior achievements, including securing Orphan Drug Designation in 2023 and Fast Track Designation in 2024.
• In April 2025, Gilead Sciences shared positive outcomes from the Phase 3 ASCENT-04/KEYNOTE-D19 trial. The study revealed that combining Trodelvy® (sacituzumab govitecan-hziy) with Keytruda® (pembrolizumab) significantly extended progression-free survival in patients with metastatic triple-negative breast cancer (mTNBC) exhibiting PD-L1 expression (CPS ≥ 10), compared to treatment with chemotherapy plus Keytruda alone.

Triple Negative Breast Cancer Overview

Triple-Negative Breast Cancer is defined as the heterogeneous breast cancer phenotype where the estrogen and progesterone receptor are negative, as assessed by immunohistochemistry (IHC), and there is a lack of overexpression of HER2, as assessed by immunohistochemistry (IHC), or the absence of its gene amplification, as assessed by fluorescence in situ hybridization technique. The epidemiological risk factor profiles also vary between TNBC (ER-PR-HER2-) and other breast cancers.

Through various secondary domains, it can be concluded that TNBC affects females. TNBC Symptoms include Breast pain or redness, A lump or mass in the breast and a nipple that turns inward or has a discharge.

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Triple Negative Breast Cancer Market

The Triple Negative Breast Cancer market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Triple Negative Breast Cancer market trends by analyzing the impact of current Triple Negative Breast Cancer therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.

This segment gives a thorough detail of the Triple Negative Breast Cancer market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Triple Negative Breast Cancer market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

Triple-negative breast cancer (TNBC) lacks hormone receptors and HER2 expression, rendering it unresponsive to hormonal and HER2-targeted therapies. Consequently, chemotherapy remains the primary treatment, especially for metastatic cases, with neoadjuvant or adjuvant therapy often preceding first-line treatment for advanced disease. If progression occurs, second-line and further therapies are employed. Immunotherapy, notably PD-1/PD-L1 inhibitors, is increasingly utilized to stimulate anti-tumor immunity in metastatic TNBC.

For early-stage TNBC, KEYTRUDA (pembrolizumab), a PD-1 inhibitor, is now standard when combined with neoadjuvant chemotherapy and continued as adjuvant monotherapy. It is also approved with chemotherapy for locally recurrent or metastatic PD-L1-positive TNBC. In BRCA-mutated cases, PARP inhibitors like LYNPARZA and TALZENNA target faulty DNA repair mechanisms. TRODELVY, a TROP-2-directed antibody-drug conjugate, treats recurrent or refractory metastatic TNBC. While TECENTRIQ was withdrawn in the US after failing confirmatory trials, it remains available elsewhere.

Taxane-based regimens continue as standard care, often paired with immunotherapy for PD-L1-positive tumors. Platinum-based options are used selectively due to toxicity and modest benefits. Despite these advances, TNBC remains aggressive, highlighting the urgent need for novel therapies. Promising pipeline drugs such as DATROWAY, Adagloxad Simolenin, PADCEV, BNT327/PM8002, and Tilarginine may expand future treatment options.

Triple Negative Breast Cancer Epidemiology

The Triple Negative Breast Cancer epidemiology section provides insights into the historical and current Triple Negative Breast Cancer patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Triple Negative Breast Cancer market report also provides the diagnosed patient pool, trends, and assumptions.

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Triple Negative Breast Cancer Drugs Uptake

This section focuses on the uptake rate of the potential Triple Negative Breast Cancer drugs recently launched in the Triple Negative Breast Cancer market or expected to be launched in 2020-2034. The analysis covers the Triple Negative Breast Cancer market uptake by drugs, patient uptake by therapies, and sales of each drug.

Triple Negative Breast Cancer Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Triple Negative Breast Cancer market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Triple Negative Breast Cancer Pipeline Development Activities

The Triple Negative Breast Cancer report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Triple Negative Breast Cancer key players involved in developing targeted therapeutics.

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Triple Negative Breast Cancer Therapeutics Assessment

Major key companies are working proactively in the Triple Negative Breast Cancer Therapeutics market to develop novel therapies which will drive the Triple Negative Breast Cancer treatment markets in the upcoming years are Johnson & Johnson Private Limited, Cipla Inc, Abbott, AbbVie Inc, Merck KGaA, Sun Pharmaceutical, Aurobindo Pharma, Lupin, Hikma Pharmaceuticals PLC, Amneal Pharmaceuticals LLC., Pfizer Inc, Mylan N.V., Novartis AG, Bristol-Myers Squibb Company, GSK plc, Bayer AG, AstraZeneca, Gilead Science, Infinity Pharmaceuticals, HiberCell, Immunomedics, HiberCell, CytoDyn, and Many Others.

Learn more about the emerging Triple Negative Breast Cancer therapies & key companies @ Triple Negative Breast Cancer Clinical Trials and FDA Approvals

Triple Negative Breast Cancer Report Key Insights

1. Triple Negative Breast Cancer Patient Population

2. Triple Negative Breast Cancer Market Size and Trends

3. Key Cross Competition in the Triple Negative Breast Cancer Market

4. Triple Negative Breast Cancer Market Dynamics (Key Drivers and Barriers)

5. Triple Negative Breast Cancer Market Opportunities

6. Triple Negative Breast Cancer Therapeutic Approaches

7. Triple Negative Breast Cancer Pipeline Analysis

8. Triple Negative Breast Cancer Current Treatment Practices/Algorithm

9. Impact of Emerging Therapies on the Triple Negative Breast Cancer Market

Table of Contents

1. Key Insights

2. Executive Summary

3. Triple Negative Breast Cancer Competitive Intelligence Analysis

4. Triple Negative Breast Cancer Market Overview at a Glance

5. Triple Negative Breast Cancer Disease Background and Overview

6. Triple Negative Breast Cancer Patient Journey

7. Triple Negative Breast Cancer Epidemiology and Patient Population

8. Triple Negative Breast Cancer Treatment Algorithm, Current Treatment, and Medical Practices

9. Triple Negative Breast Cancer Unmet Needs

10. Key Endpoints of Triple Negative Breast Cancer Treatment

11. Triple Negative Breast Cancer Marketed Products

12. Triple Negative Breast Cancer Emerging Therapies

13. Triple Negative Breast Cancer Seven Major Market Analysis

14. Attribute Analysis

15. Triple Negative Breast Cancer Market Outlook (7 major markets)

16. Triple Negative Breast Cancer Access and Reimbursement Overview

17. KOL Views on the Triple Negative Breast Cancer Market

18. Triple Negative Breast Cancer Market Drivers

19. Triple Negative Breast Cancer Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

About DelveInsight

DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.

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